The Top 60 Cartoon Characters of All Time

1. Homer Simpson (The Simpsons)
2. Mr. Peabody and Sherman (Rocky and Bullwinkle)
3. Wile E. Coyote (Looney Tunes) (includes his most notable incarnation in the Roadrunner series, as well as the Super Genius foil to Bugs Bunny and as Ralph Wolf versus Sam Sheepdog)
4. Bullwinkle J. Moose (Rocky and Bullwinkle)
5. Pepe Le Pew (Looney Tunes)
6. Milhouse Van Houten (The Simpsons)
7. Yosemite Sam (Looney Tunes)
8. Snidely Whiplash (Rocky and Bullwinkle)
9. Daffy Duck (Looney Tunes)
10. Bugs Bunny (Looney Tunes)
11. Rocket J. Squirrel (Rocky and Bullwinkle)
12. SpongeBob SquarePants
13. Augie Doggie and Doggie Daddy (Hanna-Barbera)
14. Tigger
15. Charlie Brown
16. Ralph Wiggum (The Simpsons)
17. Droopy Dog
18. Tom the Cat (Hanna-Barbera)*
19. George of the Jungle
20. Foghorn Leghorn (Looney Tunes)
21. Snagglepuss (Hanna-Barbera)
22. The Tasmanian Devil (Looney Tunes)
23. Hank Hill (King of the Hill)
24. Underdog
25. Captain Caveman (Hanna-Barbera)
26. Speedy Gonzalez (Looney Tunes)
27. J. Wellington Wimpy (Popeye)
28. Elmer Fudd (Looney Tunes)
29. Space Ghost (Hanna-Barbera)
30. Boris Badenov and Natasha Fatale (Rocky and Bullwinkle)
31. Ren and Stimpy
32. Sylvester J. Pussycat Senior (Looney Tunes)
33. George Jetson (Hanna-Barbera)
34. Mighty Mouse
35. Patrick the Starfish (SpongeBob Squarepants)
36. Ned Flanders (The Simpsons)
37. Mushmouth (Fat Albert)
38. Beavis and Butthead
39. Sandy Cheeks (SpongeBob SquarePants)
40. Maggie Simpson (The Simpsons)
41. Grape Ape (Hanna-Barbera)
42. Woody Woodpecker
43. Porky Pig (Looney Tunes)
44. Astro (Tralfaz) Jetson (Hanna-Barbera)
45. Marvin the Martian (Looney Tunes)
46. Hong Kong Phooey (Hanna-Barbera)
47. Felix the Cat
48. Nelson Muntz (The Simpsons)
49. Roger Rabbit
50. Inspector Gadget
51. Jabberjaw (Hanna-Barbera)
52. Shaggy (Hanna-Barbera)
53. Huckleberry Hound (Hanna-Barbera)
54. Mr. Smee (Peter Pan)
55. Dumb Donald (Fat Albert)
56. Yogi Bear (Hanna-Barbera)
57. Muttley (Hanna-Barbera)
58. The Pink Panther
59. Disco Stu (The Simpsons)
60. Monkey (Dial M for Monkey)

*I really don't want to rank Tom this highly because Tom and Jerry was really never that funny, but the fraction of a second when Tom gets his tail caught in a mousetrap or sits on a tack and then screams like a human being is always one of the funniest things I'll ever see.